Dr. Stoltz’s research focuses on the pathogenesis of cystic fibrosis related airway disease with a particular emphasis on studying airway epithelial and smooth muscle cells, the role of paraoxonases (PONs) on Pseudomonas aeruginosa quorum-sensing regulation, mucociliary clearance, and advanced airway imaging modalities and analysis. In collaboration with other investigators at the University of Iowa, Dr. Stoltz has overseen the development of the CF pig model for over 15 years. He directed and participated in the development of the surgical correction of the meconium ileus
phenotype followed by the genetic correction of this phenotype. A major goal of his current research is to better understand the role of CFTR in airway epithelial, mucus, and smooth muscle cell biology, using a variety of techniques and complementary approaches.