Dr. Weiner is an active translational cancer investigator who has been on the faculty at the University of Iowa since 1989. He served as Director of the Holden Comprehensive Cancer Center (HCCC) from 1999 until April 2023 and led the Cancer Center to recognition as an NCI-designated comprehensive cancer center in 2000. This designation was renewed in 2005, 2011, 2016 and 2021.
Dr. Weiner’s translational research centers on the relationship between the tumor microenvironment and cancer immunotherapy. This includes laboratory projects exploring novel approaches to cancer immunotherapy and evaluation of the mechanisms of response and resistance to cancer. The laboratory uses molecular and cellular techniques as well as model systems and is extensively involved in analysis of correlative clinical samples.