Center Affiliation and Expertise: Inflammation and Innate Immunity Thematic Area
Dr. Klesney-Tait’s research focuses on the role of neutrophils in the regulation of inflammation. Her laboratory utilizes animal models of pneumonia, sepsis and reperfusion to study neutrophil function. In particular, they are exploring the Triggering Receptor Expressed on Myeloid cells 1 (TREM-1), an innate immune receptor expressed on neutrophils that functions as an amplifier of proinflammatory signaling.